'In Silico' Simulation of Biological Processes (Novartis Foundation Symposia)
| Author | : | |
| Rating | : | 4.77 (711 Votes) |
| Asin | : | 0470844809 |
| Format Type | : | paperback |
| Number of Pages | : | 270 Pages |
| Publish Date | : | 2016-08-14 |
| Language | : | English |
DESCRIPTION:
Further chapters build on these approaches to show how computerized models of intact cells can be developed. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. Instead, computer technologies must now be used to perform this integration. The initial chapters deal with fundamental developments in hardware, software and mathematics that underlie current approaches to biological modelling. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions. Over recent decades vast amounts of biological data have been accumulated. These databases form a vital resource for any investigator trying to construct an integrated picture of particular biological systems.Cell signalling systems form a particularly complicated aspect of all cellular function and are important both in the understanding of basic cellular processes and in selecting targets for drug
From the Back Cover Over recent decades vast amounts of biological data have been accumulated. Instead, computer technologies must now be used to perform this integration. Finally, approaches to the computer modelling of whole organs such as the heart are presented. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions.. Next, different approaches to collating data on gene structure and function are presented. Recent approaches to integrating data on cell signalling into computer
Better simulations In 1988, at Los Alamos, I was in a research group that did simulations of hair cells in the inner ear. These were then state of the art, and involved modelling the transport of various elements like potassium across the cell boundaries.But computer hardware has improved enormously since then. Along with the understanding at the cellular level of many processes. So now, "in silico" simulations have become feasible for a wide range of biological system